Calcification of bladder wall after intravesical mitomycin C therapy: a case report and review of literature
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Keywords
bladder cancer, mitomycin, side effects
Abstract
Bladder wall calcification is an under-reported adverse effect of intravesical mitomycin C therapy. We report our experience of a man who developed extensive bladder wall calcification within three weeks of being treated with just a single 40 mg dose of intravesical mitomycin C for non-muscle invasive, low-grade transitional cell carcinoma of the bladder. To date, only six other cases were reported in the scientific literature in English, all of which used higher doses of mitomycin and had a longer time to diagnosis than this case. We compared the salient points of this case with previously reported cases.
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References
2. Pouya M, Van Cangh PJ, Wese FX, Opsomer RJ, Saleh M (1995) Calcification of the bladder wall following instillation of mitomycin C. Apropos of a case report. Acta Urol Belg. 63(4):19-21.
3. Alter AJ, Malek GH. Bladder wall calcification after topical mitomycin C (1987) J Urol. 138(5):1239-1240.
4. Liu CC, Chou YH, Huang CH, Tsai KB (2001) Bladder wall calcification after intravesical chemotherapy with mitomycin C: a case report. Kaohsiung J Med Sci. 17(5):274-277.
5. Fiore AA, Iorio B, Vennarecci G, et al. (1993) Papillary-like bladder calcifications following intravescical mitomycin C. A case report. Minerva Urol Nefrol. 45(4):171-173.
6. Llopis M, Moreno J, Botella R, Algado M (1993) Incrusted cystitis after intravesical mitomycin C treatment. Acta Urol Belg. 61(3):21-23.
7. Drago PC, Badalament RA, Lucas J, Drago JR (1989) Bladder wall calcification after intravesical mitomycin C treatment of superficial bladder cancer. J Urol. 142(4):1071-1072.